Photodynamic Therapy (PDT) for Skin Cancer
Non-surgical, light-based treatment for actinic keratoses and early skin cancers.
PDT: A Safe and Effective Option for Skin Cancer and Skin Conditions
Photodynamic Therapy (PDT) is an advanced medical treatment that uses a combination of light energy, a photosensitizing agent, and oxygen to target and destroy abnormal skin cells, including certain types of skin cancer and precancerous lesions like actinic keratoses (AKs). This minimally invasive, non-surgical approach is performed at Phoenix Surgical Dermatology Group by our experienced, board-certified dermatologists.
Whether you are seeking treatment for
precancerous growths,
early skin cancers, or other dermatologic conditions like
acne or
age spots, PDT offers effective results with minimal downtime.
What Is Photodynamic Therapy (PDT)?
Photodynamic therapy works by applying a photosensitizing agent directly to the skin, which is absorbed preferentially by abnormal or damaged cells. Once the agent has adequately penetrated these cells, the treated area is exposed to a specific wavelength of light, which activates the agent and generates a form of toxic oxygen that destroys the abnormal cells.
PDT selectively targets abnormal tissue while sparing surrounding healthy skin, making it an ideal option for
non-invasive treatment of certain skin conditions.
What Conditions Can Be Treated with Photodynamic Therapy?
PDT is effective for a variety of dermatologic conditions and is often used as a treatment alternative to surgery or other invasive methods.
Common Conditions Treated with PDT:
- Actinic keratoses
(precancerous lesions)
- Basal cell carcinoma
(superficial types)
- Squamous cell carcinoma
in situ (Bowen’s disease)
- Acne vulgaris (especially resistant or cystic acne)
- Age spots (solar lentigines)
- Rosacea
- Enlarged pores and textural irregularities
- Improvement of acne scars and photodamage
Your board-certified dermatologist at Phoenix Surgical Dermatology Group will assess your condition to determine if PDT is the right treatment option for you.
How Is Photodynamic Therapy Performed?
The PDT Process Includes:
Application of the Photosensitizing Agent:
- A medicated solution is applied directly to the area being treated.
- The solution is allowed to incubate for a period of time (usually between
30 to 90 minutes, depending on the condition being treated).
Activation with Light Exposure:
- The treated area is exposed to a specific wavelength of
blue or red light, which activates the photosensitizing agent.
- This process generates a chemical reaction that produces oxygen radicals to destroy abnormal cells.
Post-Treatment Care:
- After the procedure, a dressing may be applied.
- Patients are advised to
avoid sun exposure and bright light for at least
48 hours after treatment to prevent additional sensitivity.
Is Photodynamic Therapy Painful?
Most patients tolerate PDT well, but some may experience mild to moderate discomfort, including:
- Stinging or burning sensations during light exposure
- Temporary redness, swelling, or irritation of the treated area
Pain management options are available, and your dermatologist will work with you to ensure the procedure is as comfortable as possible.
How Much Downtime Should I Expect After PDT?
The amount of downtime varies depending on the treated condition and the individual's skin sensitivity. Most patients experience:
- Redness, swelling, and mild peeling
- Possible
skin sensitivity to light for
48 hours post-treatment
- Full healing generally occurs within
3–7 days, though in some cases, it may take up to a week
It is essential to
strictly avoid direct sunlight and bright indoor lighting during the initial recovery period.
How Effective Is Photodynamic Therapy for Actinic Keratoses and Skin Cancer?
PDT has proven to be highly effective, especially for treating actinic keratoses (AKs). Studies have shown that PDT can achieve complete clearance rates of up to 95% for AKs, outperforming other common treatments like cryotherapy (freezing) or topical medications.
The precision of PDT makes it an excellent choice for treating
large areas of damaged skin or for patients seeking a non-surgical approach.
Is Photodynamic Therapy the Same as Blue Light Therapy?
While both PDT and blue light therapy use light to treat skin conditions, they are
not the same treatment.
Photodynamic Therapy (PDT)
Uses a photosensitizing agent plus light to activate a chemical reaction that destroys abnormal cells.
Commonly used for
skin cancers, actinic keratoses, and acne.
Blue Light Therapy
Uses light alone, without a photosensitizing agent, to target acne-causing bacteria and reduce inflammation.
Often used for
mild to moderate acne treatment.
Is Photodynamic Therapy Covered by Insurance?
Insurance coverage for PDT generally depends on the medical necessity of the treatment.
Typically Covered by Insurance If Used To Treat:
Insurance may
not cover PDT for cosmetic treatments, such as for
wrinkles, enlarged pores, or age spots. We recommend checking with your insurance provider to confirm your coverage and potential out-of-pocket costs.
Frequently Asked Questions About Photodynamic Therapy
Is PDT effective for all skin cancers?
PDT is primarily used for superficial skin cancers, such as superficial basal cell carcinoma and squamous cell carcinoma in situ. It is not recommended for deeper or invasive skin cancers.
How many PDT treatments will I need?
The number of treatments varies based on the condition being treated. Many patients with actinic keratoses require one or two sessions spaced several weeks apart. Your dermatologist will create a personalized treatment plan for you.
What should I avoid after PDT?
Avoid sunlight, tanning beds, bright indoor lights, and heat exposure for at least 48 hours. Use a broad-spectrum sunscreen and follow your dermatologist’s aftercare instructions carefully.
Can I resume normal activities after PDT?
Most patients can return to daily activities within a few days, but should avoid direct sunlight and strenuous activities during the initial recovery period.
Schedule Your Photodynamic Therapy Consultation Today
If you have
actinic keratoses, early-stage skin cancers, or other skin concerns, contact
Phoenix Surgical Dermatology Group to learn more about
photodynamic therapy and find out if it’s right for you. Our
board-certified dermatologists are dedicated to providing safe, effective, and personalized treatment options for every patient.
